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王聪

年级: 2016级博士  |  Email93443925@qq.com  |  家乡吉林

教育背景(从本科填)

  2001年-2006年北华大学临床医学专业本科

  2008年-2011年大理大学病原生物学专业硕士

  2016年-2019年复旦大学病原生物学专业博士

研究方向

LASV的感染机制及抗病毒药物研究

研究生期间发表论文

1: Xia S, Xu W, Wang Q, Wang C, Hua C, Li W, Lu L, Jiang S. Peptide-Based

Membrane Fusion Inhibitors Targeting HCoV-229E Spike Protein HR1 and HR2

Domains. Int J Mol Sci. 2018 Feb 6;19(2):487. doi: 10.3390/ijms19020487. PMID:

29415501; PMCID: PMC5855709.


2: Wang Q, Su S, Xue J, Yu F, Pu J, Bi W, Xia S, Meng Y, Wang C, Yang W, Xu W,

Zhu Y, Zheng Q, Qin C, Jiang S, Lu L. An amphipathic peptide targeting the gp41

cytoplasmic tail kills HIV-1 virions and infected cells. Sci Transl Med. 2020

Jun 3;12(546):eaaz2254. doi: 10.1126/scitranslmed.aaz2254. PMID: 32493792.


3: Fu Y, Li P, Xu W, Liu Z, Wang C, Wang Q, Tang J, Li W, Lu L, Jiang S.

Chemically Modified Bovine β-Lactoglobulin as a Broad-Spectrum Influenza Virus

Entry Inhibitor with the Potential to Combat Influenza Outbreaks. Viruses. 2022

Sep 16;14(9):2055. doi: 10.3390/v14092055. PMID: 36146861; PMCID: PMC9506557.


4: Pu J, He X, Xu W, Wang C, Lan Q, Hua C, Wang K, Lu L, Jiang S. The Analogs of

Furanyl Methylidene Rhodanine Exhibit Broad-Spectrum Inhibitory and Inactivating

Activities against Enveloped Viruses, including SARS-CoV-2 and Its Variants.

Viruses. 2022 Feb 27;14(3):489. doi: 10.3390/v14030489. PMID: 35336896; PMCID:

PMC8954792.


5: Xia S, Lan Q, Pu J, Wang C, Liu Z, Xu W, Wang Q, Liu H, Jiang S, Lu L. Potent

MERS-CoV Fusion Inhibitory Peptides Identified from HR2 Domain in Spike Protein

of Bat Coronavirus HKU4. Viruses. 2019 Jan 14;11(1):56. doi: 10.3390/v11010056.

PMID: 30646495; PMCID: PMC6357153.


6: Zhang X, Wang C, Chen B, Wang Q, Xu W, Ye S, Jiang S, Zhu Y, Zhang R. Crystal

Structure of Refolding Fusion Core of Lassa Virus GP2 and Design of Lassa Virus

Fusion Inhibitors. Front Microbiol. 2019 Aug 13;10:1829. doi:

10.3389/fmicb.2019.01829. PMID: 31456769; PMCID: PMC6700223.


7: Wang C, Hua C, Xia S, Li W, Lu L, Jiang S. Combining a Fusion Inhibitory

Peptide Targeting the MERS-CoV S2 Protein HR1 Domain and a Neutralizing Antibody

Specific for the S1 Protein Receptor-Binding Domain (RBD) Showed Potent

Synergism against Pseudotyped MERS-CoV with or without Mutations in RBD.

Viruses. 2019 Jan 6;11(1):31. doi: 10.3390/v11010031. PMID: 30621343; PMCID:

PMC6356712.


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