教育背景

2010年-2014年宁波大学生物工程专业本科

2016年-2019年复旦大学病原生物学专业硕士

学位论文及研究生期间发表论文

学位论文题目《 Ⅲ型胶原蛋白肽及其重组蛋白的功能和机制研究》

发表论文：

Hua, C., Zhu, Y., Xu, W., Ye, S., Zhang, R., Lu, L., et al. (2019). Characterization by high-resolution crystal structure analysis of a triple-helix region of human collagen type III with potent cell adhesion activity. Biochem Biophys Res Commun 508(4), 1018-1023. doi: 10.1016/j.bbrc.2018.12.018.

Hua, C., Zhu, Y., Wu, C.Q., Si, L.L., Wang, Q., Sui, L., et al. (2019a). The Underlying Mechanism of 3-Hydroxyphthalic Anhydride-Modified Bovine Beta-Lactoglobulin to Block Human Papillomavirus Entry Into the Host Cell. Frontiers in Microbiology 10. doi: ARTN 218810.3389/fmicb.2019.02188.

Su, S., Ma, Z., Hua, C., Li, W., Lu, L., and Jiang, S. (2017a). Adding an Artificial Tail-Anchor to a Peptide-Based HIV-1 Fusion Inhibitor for Improvement of Its Potency and Resistance Profile. Molecules 22(11). doi: 10.3390/molecules22111996.

Su, S., Wang, Q., Xu, W., Yu, F., Hua, C., Zhu, Y., et al. (2017b). A novel HIV-1 gp41 tripartite model for rational design of HIV-1 fusion inhibitors with improved antiviral activity. AIDS 31(7), 885-894. doi: 10.1097/QAD.0000000000001415.

Wang, C., Hua, C., Xia, S., Li, W., Lu, L., and Jiang, S. (2019). Combining a Fusion Inhibitory Peptide Targeting the MERS-CoV S2 Protein HR1 Domain and a Neutralizing Antibody Specific for the S1 Protein Receptor-Binding Domain (RBD) Showed Potent Synergism against Pseudotyped MERS-CoV with or without Mutations in RBD. Viruses 11(1). doi: 10.3390/v11010031.

Wang, Q., Dai, Y., Sun, Z., Su, X., Yu, Y., Hua, C., et al. (2017). HIV-1 Env DNA prime plus gp120 and gp70-V1V2 boosts induce high level of V1V2-specific IgG and ADCC responses and low level of Env-specific IgA response: implication for improving RV144 vaccine regimen. Emerg Microbes Infect 6(11), e102. doi: 10.1038/emi.2017.90.

Xia, S., Xu, W., Wang, Q., Wang, C., Hua, C., Li, W., et al. (2018). Peptide-Based Membrane Fusion Inhibitors Targeting HCoV-229E Spike Protein HR1 and HR2 Domains. Int J Mol Sci 19(2). doi: 10.3390/ijms19020487.

Xu, W., Dai, Y., Hua, C., Wang, Q., Zou, P., Deng, Q., et al. (2017a). Genomic signature analysis of the recently emerged highly pathogenic A(H5N8) avian influenza virus: implying an evolutionary trend for bird-to-human transmission. Microbes Infect 19(12), 597-604. doi: 10.1016/j.micinf.2017.08.006.

Xu, W., Li, H., Wang, Q., Hua, C., Zhang, H., Li, W., et al. (2017b). Advancements in Developing Strategies for Sterilizing and Functional HIV Cures. Biomed Res Int 2017, 6096134. doi: 10.1155/2017/6096134.

Xu, W., Pu, J., Su, S., Hua, C., Su, X., Wang, Q., et al. (2019). Revisiting the mechanism of enfuvirtide and designing an analog with improved fusion inhibitory activity by targeting triple sites in gp41. AIDS 33(10), 1545-1555. doi: 10.1097/QAD.0000000000002208.

Yang, W., Sun, Z., Hua, C., Wang, Q., Xu, W., Deng, Q., et al. (2018). Chidamide, a histone deacetylase inhibitor-based anticancer drug, effectively reactivates latent HIV-1 provirus. Microbes Infect 20(9-10), 626-634. doi: 10.1016/j.micinf.2017.10.003.

获奖情况

学业奖学金

上海市互联网＋创新创业大赛银奖

毕业去向

留组